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Presence, persistence and effects of pre-treatment HIV-1 drug resistance variants detected using next generation sequencing: A Retrospective longitudinal study from rural coastal Kenya

BACKGROUND: The epidemiology of HIV-1 drug resistance (HIVDR) determined by Sanger capillary sequencing, has been widely studied. However, much less is known about HIVDR detected using next generation sequencing (NGS) methods. We aimed to determine the presence, persistence and effect of pre-treatme...

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Detalles Bibliográficos
Autores principales: Hassan, Amin S., Bibby, David F., Mwaringa, Shalton M., Agutu, Clara A., Ndirangu, Kennedy K., Sanders, Eduard J., Cane, Patricia A., Mbisa, Jean L., Berkley, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373901/
https://www.ncbi.nlm.nih.gov/pubmed/30759103
http://dx.doi.org/10.1371/journal.pone.0210559

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