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Quantitative systems pharmacology of interferon alpha administration: A multi-scale approach

The therapeutic effect of a drug is governed by its pharmacokinetics which determine the downstream pharmacodynamic response within the cellular network. A complete understanding of the drug-effect relationship therefore requires multi-scale models which integrate the properties of the different phy...

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Detalles Bibliográficos
Autores principales:	Kalra, Priyata, Brandl, Julian, Gaub, Thomas, Niederalt, Christoph, Lippert, Jörg, Sahle, Sven, Küpfer, Lars, Kummer, Ursula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374012/ https://www.ncbi.nlm.nih.gov/pubmed/30759154 http://dx.doi.org/10.1371/journal.pone.0209587

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