A novel luciferase-based assay for the detection of Chimeric Antigen Receptors

Chimeric Antigen Receptor-T (CAR-T) cell immunotherapy has produced dramatic responses in hematologic malignancies. One of the challenges in the field is the lack of a simple assay for the detection of CARs on the surface of immune effector cells. In this study, we describe a novel luciferase-based...

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Detalles Bibliográficos
Autores principales: Gopalakrishnan, Ramakrishnan, Matta, Hittu, Choi, Sunju, Natarajan, Venkatesh, Prins, Ruben, Gong, Songjie, Zenunovic, Arta, Narasappa, Nell, Patel, Fatima, Prakash, Rekha, Chaudhary, Vishan, Sikri, Varun, Chitnis, Saurabh Deepak, Kochegarov, Andrei, Wang, Dan, Falat, Magdalena, Kahn, Michael, Keerthipati, Pooja Smruthi, Sharma, Naman, Lenka, Jyotirmayee, Stieben, Tomas Meza, Braun, Jason, Batra, Ankita, Purvis, Katelyn, Ito, Kenta, Lee, Jae Han, Jeronimo, Alberto, Zamora, Hannalei Mae, Membreno, Allen, Qiu, Queenie, Peshin, Supriya, Namburu, Lalith, Chaudhary, Preet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374361/
https://www.ncbi.nlm.nih.gov/pubmed/30760795
http://dx.doi.org/10.1038/s41598-018-38258-z

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