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Targeting autophagy potentiates antitumor activity of Met-TKIs against Met-amplified gastric cancer
Met tyrosine kinase inhibitors (Met-TKIs) subjected to ongoing clinical trials are a promising option for Met-amplified gastric cancer (GC), but how to optimize their antitumor activity especially with combination schemes remains unclear. Since autophagy is known to be initiated by Met-TKIs, we inve...
Autores principales: | Lin, Xiaoting, Peng, Zhi, Wang, Xiaojuan, Zou, Jianling, Chen, Dongshao, Chen, Zuhua, Li, Zhongwu, Dong, Bin, Gao, Jing, Shen, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374362/ https://www.ncbi.nlm.nih.gov/pubmed/30760701 http://dx.doi.org/10.1038/s41419-019-1314-x |
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