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Reduced mitochondrial respiration and increased calcium deposits in the EDL muscle, but not in soleus, from 12-week-old dystrophic mdx mice
Mitochondria play an important role in providing ATP for muscle contraction. Muscle physiology is compromised in Duchenne muscular dystrophy (DMD) and several studies have shown the involvement of bioenergetics. In this work we investigated the mitochondrial physiology in fibers from fast-twitch mus...
Autores principales: | Gaglianone, Rhayanna B., Santos, Anderson Teixeira, Bloise, Flavia Fonseca, Ortiga-Carvalho, Tania Maria, Costa, Manoel Luis, Quirico-Santos, Thereza, da Silva, Wagner Seixas, Mermelstein, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374364/ https://www.ncbi.nlm.nih.gov/pubmed/30760802 http://dx.doi.org/10.1038/s41598-019-38609-4 |
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