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The monoclonal antibody EPR1614Y against the stem cell biomarker keratin K15 lacks specificity and reacts with other keratins

Keratin 15 (K15), a type I keratin, which pairs with K5 in epidermis, has been used extensively as a biomarker for stem cells. Two commercial antibodies, LHK15, a mouse monoclonal and EPR1614Y, a rabbit monoclonal, have been widely employed to study K15 expression. Here we report differential reacti...

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Detalles Bibliográficos
Autores principales: Aldehlawi, Hebah, Niemiec, Katarzyna A., Avisetti, Deepa R., Lalli, Anand, Teh, Muy-Teck, Waseem, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374370/
https://www.ncbi.nlm.nih.gov/pubmed/30760780
http://dx.doi.org/10.1038/s41598-018-38163-5

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