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Chronic sleep restriction in the rotenone Parkinson’s disease model in rats reveals peripheral early-phase biomarkers
Parkinson’s disease (PD) is a chronic disorder that presents a range of premotor signs, such as sleep disturbances and cognitive decline, which are key non-motor features of the disease. Increasing evidence of a possible association between sleep disruption and the neurodegenerative process suggests...
Autores principales: | Fagotti, Juliane, Targa, Adriano D. S., Rodrigues, Lais S., Noseda, Ana Carolina D., Dorieux, Flávia W. C., Scarante, Franciele F., Ilkiw, Jessica L., Louzada, Fernando M., Chowdhury, Namrata R., van der Veen, Daan R., Middleton, Benita, Pennings, Jeroen L. A., Swann, Jonathan R., Skene, Debra J., Lima, Marcelo M. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374389/ https://www.ncbi.nlm.nih.gov/pubmed/30760786 http://dx.doi.org/10.1038/s41598-018-37657-6 |
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