Genomic characterization of genes encoding histone acetylation modulator proteins identifies therapeutic targets for cancer treatment

A growing emphasis in anticancer drug discovery efforts has been on targeting histone acetylation modulators. Here we comprehensively analyze the genomic alterations of the genes encoding histone acetylation modulator proteins (HAMPs) in the Cancer Genome Atlas cohort and observe that HAMPs have a h...

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Detalles Bibliográficos
Autores principales: Hu, Zhongyi, Zhou, Junzhi, Jiang, Junjie, Yuan, Jiao, Zhang, Youyou, Wei, Xuepeng, Loo, Nicki, Wang, Yueying, Pan, Yutian, Zhang, Tianli, Zhong, Xiaomin, Long, Meixiao, Montone, Kathleen T., Tanyi, Janos L., Fan, Yi, Wang, Tian-Li, Shih, Ie-Ming, Hu, Xiaowen, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374416/
https://www.ncbi.nlm.nih.gov/pubmed/30760718
http://dx.doi.org/10.1038/s41467-019-08554-x

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