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Insulin Receptor deletion in S100a4-lineage cells accelerates age-related bone loss

Type I and Type II Diabetes dramatically impair skeletal health. Altered Insulin Receptor (IR) signaling is a common feature of both diseases, and insulin has potent bone anabolic functions. Several previous studies have demonstrated that loss of IR in bone cells results in disrupted bone homeostasi...

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Detalles Bibliográficos
Autores principales:	Studentsova, Valentina, Knapp, Emma, Loiselle, Alayna E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374520/ https://www.ncbi.nlm.nih.gov/pubmed/30805422 http://dx.doi.org/10.1016/j.bonr.2019.100197

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