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Dysregulation of autophagy in the central nervous system of sheep naturally infected with classical scrapie

Autophagy is a dynamic cellular mechanism involved in protein and organelle turnover through lysosomal degradation. Autophagy regulation modulates the pathologies associated with many neurodegenerative diseases. Using sheep naturally infected with scrapie as a natural animal model of prion diseases,...

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Detalles Bibliográficos
Autores principales:	López-Pérez, Óscar, Otero, Alicia, Filali, Hicham, Sanz-Rubio, David, Toivonen, Janne M., Zaragoza, Pilar, Badiola, Juan J., Bolea, Rosa, Martín-Burriel, Inmaculada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374525/ https://www.ncbi.nlm.nih.gov/pubmed/30760781 http://dx.doi.org/10.1038/s41598-019-38500-2

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