Dose-Dependent Differences in HIV Inhibition by Different Interferon Alpha Subtypes While Having Overall Similar Biologic Effects

Type I interferons (IFNs) are key players in the antiviral immune response. Interferon alpha (IFN-α) belongs to this class of IFNs and comprises 12 subtypes that differ from each other in their binding affinities for a common receptor and, thus, in their signaling potencies. Recent data suggest that...

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Detalles Bibliográficos
Autores principales: Schlaepfer, Erika, Fahrny, Audrey, Gruenbach, Maarja, Kuster, Stefan P., Simon, Viviana, Schreiber, Gideon, Speck, Roberto F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374594/
https://www.ncbi.nlm.nih.gov/pubmed/30760614
http://dx.doi.org/10.1128/mSphere.00637-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374594/
https://www.ncbi.nlm.nih.gov/pubmed/30760614
http://dx.doi.org/10.1128/mSphere.00637-18

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