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Dose-Dependent Differences in HIV Inhibition by Different Interferon Alpha Subtypes While Having Overall Similar Biologic Effects
Type I interferons (IFNs) are key players in the antiviral immune response. Interferon alpha (IFN-α) belongs to this class of IFNs and comprises 12 subtypes that differ from each other in their binding affinities for a common receptor and, thus, in their signaling potencies. Recent data suggest that...
Autores principales: | Schlaepfer, Erika, Fahrny, Audrey, Gruenbach, Maarja, Kuster, Stefan P., Simon, Viviana, Schreiber, Gideon, Speck, Roberto F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374594/ https://www.ncbi.nlm.nih.gov/pubmed/30760614 http://dx.doi.org/10.1128/mSphere.00637-18 |
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