Synthesis of a miniaturized [FeFe] hydrogenase model system

The reaction occurring during artificial maturation of [FeFe] hydrogenase has been recreated using molecular systems. The formation of a miniaturized [FeFe] hydrogenase model system, generated through the combination of a [4Fe4S] cluster binding oligopeptide and an organometallic Fe complex, has bee...

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Detalles Bibliográficos
Autores principales: Esmieu, Charlène, Guo, Meiyuan, Redman, Holly J., Lundberg, Marcus, Berggren, Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374738/
https://www.ncbi.nlm.nih.gov/pubmed/30667428
http://dx.doi.org/10.1039/c8dt05085f
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author Esmieu, Charlène
Guo, Meiyuan
Redman, Holly J.
Lundberg, Marcus
Berggren, Gustav
author_facet Esmieu, Charlène
Guo, Meiyuan
Redman, Holly J.
Lundberg, Marcus
Berggren, Gustav
author_sort Esmieu, Charlène
collection PubMed
description The reaction occurring during artificial maturation of [FeFe] hydrogenase has been recreated using molecular systems. The formation of a miniaturized [FeFe] hydrogenase model system, generated through the combination of a [4Fe4S] cluster binding oligopeptide and an organometallic Fe complex, has been monitored by a range of spectroscopic techniques. A structure of the final assembly is suggested based on EPR and FTIR spectroscopy in combination with DFT calculations. The capacity of this novel H-cluster model to catalyze H(2) production in aqueous media at mild potentials is verified in chemical assays.
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spelling pubmed-63747382019-03-06 Synthesis of a miniaturized [FeFe] hydrogenase model system Esmieu, Charlène Guo, Meiyuan Redman, Holly J. Lundberg, Marcus Berggren, Gustav Dalton Trans Chemistry The reaction occurring during artificial maturation of [FeFe] hydrogenase has been recreated using molecular systems. The formation of a miniaturized [FeFe] hydrogenase model system, generated through the combination of a [4Fe4S] cluster binding oligopeptide and an organometallic Fe complex, has been monitored by a range of spectroscopic techniques. A structure of the final assembly is suggested based on EPR and FTIR spectroscopy in combination with DFT calculations. The capacity of this novel H-cluster model to catalyze H(2) production in aqueous media at mild potentials is verified in chemical assays. Royal Society of Chemistry 2019-02-21 2019-01-15 /pmc/articles/PMC6374738/ /pubmed/30667428 http://dx.doi.org/10.1039/c8dt05085f Text en This journal is © The Royal Society of Chemistry 2019 http://creativecommons.org/licenses/by-nc/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported Licence (CC BY-NC 3.0)
spellingShingle Chemistry
Esmieu, Charlène
Guo, Meiyuan
Redman, Holly J.
Lundberg, Marcus
Berggren, Gustav
Synthesis of a miniaturized [FeFe] hydrogenase model system
title Synthesis of a miniaturized [FeFe] hydrogenase model system
title_full Synthesis of a miniaturized [FeFe] hydrogenase model system
title_fullStr Synthesis of a miniaturized [FeFe] hydrogenase model system
title_full_unstemmed Synthesis of a miniaturized [FeFe] hydrogenase model system
title_short Synthesis of a miniaturized [FeFe] hydrogenase model system
title_sort synthesis of a miniaturized [fefe] hydrogenase model system
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374738/
https://www.ncbi.nlm.nih.gov/pubmed/30667428
http://dx.doi.org/10.1039/c8dt05085f
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