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McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review
A rare combination of severe volume depletion and electrolyte imbalance caused by a rectal villous adenoma is often referred to as the McKittrick-Wheelock syndrome. Patients usually seek medical care because of chronic hypersecretory diarrhea and display renal failure, metabolic acidosis, hyponatrem...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374786/ https://www.ncbi.nlm.nih.gov/pubmed/30838142 http://dx.doi.org/10.1155/2019/3104187 |
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author | Caron, Mireille Dubrûle, Charles-Etienne Letarte, François Lemelin, Valéry Lafleur, Alexandre |
author_facet | Caron, Mireille Dubrûle, Charles-Etienne Letarte, François Lemelin, Valéry Lafleur, Alexandre |
author_sort | Caron, Mireille |
collection | PubMed |
description | A rare combination of severe volume depletion and electrolyte imbalance caused by a rectal villous adenoma is often referred to as the McKittrick-Wheelock syndrome. Patients usually seek medical care because of chronic hypersecretory diarrhea and display renal failure, metabolic acidosis, hyponatremia, and hypokalemia. We report the case of a 68-year-old woman who presented with this condition but showed unusual features such as severe hypokalemia and metabolic alkalosis, without diarrhea. She subsequently underwent transanal endoscopic microsurgery (TEMS), an innovative procedure in the management of large rectal adenomas. We also provide a narrative review of the literature on this rare entity. |
format | Online Article Text |
id | pubmed-6374786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-63747862019-03-05 McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review Caron, Mireille Dubrûle, Charles-Etienne Letarte, François Lemelin, Valéry Lafleur, Alexandre Case Rep Gastrointest Med Case Report A rare combination of severe volume depletion and electrolyte imbalance caused by a rectal villous adenoma is often referred to as the McKittrick-Wheelock syndrome. Patients usually seek medical care because of chronic hypersecretory diarrhea and display renal failure, metabolic acidosis, hyponatremia, and hypokalemia. We report the case of a 68-year-old woman who presented with this condition but showed unusual features such as severe hypokalemia and metabolic alkalosis, without diarrhea. She subsequently underwent transanal endoscopic microsurgery (TEMS), an innovative procedure in the management of large rectal adenomas. We also provide a narrative review of the literature on this rare entity. Hindawi 2019-01-31 /pmc/articles/PMC6374786/ /pubmed/30838142 http://dx.doi.org/10.1155/2019/3104187 Text en Copyright © 2019 Mireille Caron et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Caron, Mireille Dubrûle, Charles-Etienne Letarte, François Lemelin, Valéry Lafleur, Alexandre McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
title | McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
title_full | McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
title_fullStr | McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
title_full_unstemmed | McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
title_short | McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review |
title_sort | mckittrick-wheelock syndrome presenting with acute kidney injury and metabolic alkalosis: case report and narrative review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374786/ https://www.ncbi.nlm.nih.gov/pubmed/30838142 http://dx.doi.org/10.1155/2019/3104187 |
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