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Nanoenabled Bioseparations: Current Developments and Future Prospects

The use of nanomaterials in bioseparations has been recently introduced to overcome the drawbacks of the conventional methods. Different forms of nanomaterials, particularly magnetic nanoparticles (MNPs), carbon nanotubes (CNTs), casted nanoporous membranes, and electrospun nanofiber membranes were...

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Detalles Bibliográficos
Autores principales: Fahmy, Sherif Ashraf, Alawak, Mohamad, Brüßler, Jana, Bakowsky, Udo, El Sayed, Mayyada M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374799/
https://www.ncbi.nlm.nih.gov/pubmed/30834268
http://dx.doi.org/10.1155/2019/4983291
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author Fahmy, Sherif Ashraf
Alawak, Mohamad
Brüßler, Jana
Bakowsky, Udo
El Sayed, Mayyada M. H.
author_facet Fahmy, Sherif Ashraf
Alawak, Mohamad
Brüßler, Jana
Bakowsky, Udo
El Sayed, Mayyada M. H.
author_sort Fahmy, Sherif Ashraf
collection PubMed
description The use of nanomaterials in bioseparations has been recently introduced to overcome the drawbacks of the conventional methods. Different forms of nanomaterials, particularly magnetic nanoparticles (MNPs), carbon nanotubes (CNTs), casted nanoporous membranes, and electrospun nanofiber membranes were utilized in biological separation for the aim of production of different biomolecules such as proteins, amino acids, nucleic acids, and enzymes. This paper critically reviews the state-of-the-art efforts undertaken in this regard, with emphasis on the synthesis and performance evaluation of each nanoform. Challenges and future prospects in developing nanoenabled bioseparations are also discussed, for the purpose of highlighting potential advances in the synthesis and fabrication of novel nanomaterials as well as in the design of efficient nanoenabled processes for separating a wide spectrum of biomolecules.
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spelling pubmed-63747992019-03-04 Nanoenabled Bioseparations: Current Developments and Future Prospects Fahmy, Sherif Ashraf Alawak, Mohamad Brüßler, Jana Bakowsky, Udo El Sayed, Mayyada M. H. Biomed Res Int Review Article The use of nanomaterials in bioseparations has been recently introduced to overcome the drawbacks of the conventional methods. Different forms of nanomaterials, particularly magnetic nanoparticles (MNPs), carbon nanotubes (CNTs), casted nanoporous membranes, and electrospun nanofiber membranes were utilized in biological separation for the aim of production of different biomolecules such as proteins, amino acids, nucleic acids, and enzymes. This paper critically reviews the state-of-the-art efforts undertaken in this regard, with emphasis on the synthesis and performance evaluation of each nanoform. Challenges and future prospects in developing nanoenabled bioseparations are also discussed, for the purpose of highlighting potential advances in the synthesis and fabrication of novel nanomaterials as well as in the design of efficient nanoenabled processes for separating a wide spectrum of biomolecules. Hindawi 2019-01-29 /pmc/articles/PMC6374799/ /pubmed/30834268 http://dx.doi.org/10.1155/2019/4983291 Text en Copyright © 2019 Sherif Ashraf Fahmy et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Fahmy, Sherif Ashraf
Alawak, Mohamad
Brüßler, Jana
Bakowsky, Udo
El Sayed, Mayyada M. H.
Nanoenabled Bioseparations: Current Developments and Future Prospects
title Nanoenabled Bioseparations: Current Developments and Future Prospects
title_full Nanoenabled Bioseparations: Current Developments and Future Prospects
title_fullStr Nanoenabled Bioseparations: Current Developments and Future Prospects
title_full_unstemmed Nanoenabled Bioseparations: Current Developments and Future Prospects
title_short Nanoenabled Bioseparations: Current Developments and Future Prospects
title_sort nanoenabled bioseparations: current developments and future prospects
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374799/
https://www.ncbi.nlm.nih.gov/pubmed/30834268
http://dx.doi.org/10.1155/2019/4983291
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