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IFN-γ Reduces Epidermal Barrier Function by Affecting Fatty Acid Composition of Ceramide in a Mouse Atopic Dermatitis Model

IFN-γ is detected in chronic lesions of atopic dermatitis (AD); however, its specific role remains to be elucidated. An impaired stratum corneum barrier function is a hallmark of AD, and it is associated with a reduction in ceramides with long-chain fatty acids (FAs) in the stratum corneum. FA elong...

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Detalles Bibliográficos
Autores principales:	Kanoh, Hiroyuki, Ishitsuka, Asako, Fujine, Etsuko, Matsuhaba, Shuhei, Nakamura, Mitsuhiro, Ito, Hiroyasu, Inagaki, Naoki, Banno, Yoshiko, Seishima, Mariko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374817/ https://www.ncbi.nlm.nih.gov/pubmed/30838224 http://dx.doi.org/10.1155/2019/3030268

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