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A Novel Pentapeptide Inhibitor Reduces Amyloid Deposit Formation by Direct Interaction with hIAPP

BACKGROUNDS: The presence of amyloid deposits of human islet amyloid polypeptide (hIAPP) in islet β-cells has been associated with type 2 diabetes occurrence and islet graft failure. Self-assembly into oligomers and fibrils during the process of aggregation by hIAPP can lead to failure and depletion...

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Detalles Bibliográficos
Autores principales:	Shi, Yue, Lv, Wu, Jiao, Ao, Zhang, Chengshuo, Zhang, Jialin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374824/ https://www.ncbi.nlm.nih.gov/pubmed/30838043 http://dx.doi.org/10.1155/2019/9062032

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