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Stereoselectivity evaluation of chiral chitosan microspheres delivery system containing rac-KET in vitro and in vivo
The influence of chiral excipient D-chitosan (CS) on the stereoselective release of racemic ketoprofen (rac-KET) microspheres has been investigated in comparison to those microspheres containing individual enantiomers in vitro and in vivo. Stereoselectivity was observed in vitro release test, with R...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374939/ https://www.ncbi.nlm.nih.gov/pubmed/30744429 http://dx.doi.org/10.1080/10717544.2018.1556360 |