Design, synthesis, and biological evaluation of novel derivatives of dithiodiglycolic acid prepared via oxidative coupling of thiols

Human thioredoxin reductase 1 (TrxR1) is a selenocysteine-containing enzyme which plays a crucial role in regulating numerous redox signalling pathways within the cell. While its functioning is important in all cells, levels of TrxR1 expression are higher in cancer cells, possibly as an adaptation t...

Descripción completa

Detalles Bibliográficos
Autores principales: Bakulina, Olga, Bannykh, Anton, Jovanović, Mirna, Domračeva, Ilona, Podolski-Renić, Ana, Žalubovskis, Raivis, Pešić, Milica, Dar’in, Dmitry, Krasavin, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374954/
https://www.ncbi.nlm.nih.gov/pubmed/30746961
http://dx.doi.org/10.1080/14756366.2019.1575372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374954/
https://www.ncbi.nlm.nih.gov/pubmed/30746961
http://dx.doi.org/10.1080/14756366.2019.1575372

Ejemplares similares