CX3CR1-deficient microglia shows impaired signalling of the transcription factor NRF2: Implications in tauopathies

TAU protein aggregation is the main characteristic of neurodegenerative diseases known as tauopathies. Low-grade chronic inflammation is also another hallmark that indicates crosstalk between damaged neurons and glial cells. Previously, we have demonstrated that neurons overexpressing TAU(P301L) rel...

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Detalles Bibliográficos
Autores principales: Castro-Sánchez, Sara, García-Yagüe, Ángel J., Kügler, Sebastian, Lastres-Becker, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375000/
https://www.ncbi.nlm.nih.gov/pubmed/30769286
http://dx.doi.org/10.1016/j.redox.2019.101118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375000/
https://www.ncbi.nlm.nih.gov/pubmed/30769286
http://dx.doi.org/10.1016/j.redox.2019.101118

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