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CX3CR1-deficient microglia shows impaired signalling of the transcription factor NRF2: Implications in tauopathies
TAU protein aggregation is the main characteristic of neurodegenerative diseases known as tauopathies. Low-grade chronic inflammation is also another hallmark that indicates crosstalk between damaged neurons and glial cells. Previously, we have demonstrated that neurons overexpressing TAU(P301L) rel...
Autores principales: | Castro-Sánchez, Sara, García-Yagüe, Ángel J., Kügler, Sebastian, Lastres-Becker, Isabel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375000/ https://www.ncbi.nlm.nih.gov/pubmed/30769286 http://dx.doi.org/10.1016/j.redox.2019.101118 |
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