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Gadolinium-doped bioglass scaffolds promote osteogenic differentiation of hBMSC via the Akt/GSK3β pathway and facilitate bone repair in vivo
BACKGROUND: Biomaterial-induced osteogenesis is mainly related to hierarchically porous structures and bioactive components. Rare earth elements are well known to promote osteogenesis and stimulate bone repair; however, the underlying biological effects of gadolinium (Gd) element on bone regeneratio...
Autores principales: | Zhu, Dao-Yu, Lu, Bin, Yin, Jun-Hui, Ke, Qin-Fei, Xu, He, Zhang, Chang-Qing, Guo, Ya-Ping, Gao, You-Shui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375113/ https://www.ncbi.nlm.nih.gov/pubmed/30804672 http://dx.doi.org/10.2147/IJN.S193576 |
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