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Genetic deletion of genes in the cerebellar rhombic lip lineage can stimulate compensation through adaptive reprogramming of ventricular zone-derived progenitors

BACKGROUND: The cerebellum is a foliated posterior brain structure involved in coordination of motor movements and cognition. The cerebellum undergoes rapid growth postnataly due to Sonic Hedgehog (SHH) signaling-dependent proliferation of ATOH1+ granule cell precursors (GCPs) in the external granul...

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Detalles Bibliográficos
Autores principales:	Wojcinski, Alexandre, Morabito, Morgane, Lawton, Andrew K., Stephen, Daniel N., Joyner, Alexandra L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375182/ https://www.ncbi.nlm.nih.gov/pubmed/30764875 http://dx.doi.org/10.1186/s13064-019-0128-y

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