Genome-wide methylation profiling and copy number analysis in atypical fibroxanthomas and pleomorphic dermal sarcomas indicate a similar molecular phenotype

BACKGROUND: Atypical fibroxanthomas (AFX) and pleomorphic dermal sarcomas (PDS) are lesions of the skin with overlapping histologic features and unspecific molecular traits. PDS behaves aggressive compared to AFX. Thus, a precise delineation, although challenging in some instances, is relevant. METH...

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Detalles Bibliográficos
Autores principales: Koelsche, Christian, Stichel, Damian, Griewank, Klaus G., Schrimpf, Daniel, Reuss, David E., Bewerunge-Hudler, Melanie, Vokuhl, Christian, Dinjens, Winand N. M., Petersen, Iver, Mittelbronn, Michel, Cuevas-Bourdier, Adrian, Buslei, Rolf, Pfister, Stefan M., Flucke, Uta, Mechtersheimer, Gunhild, Mentzel, Thomas, von Deimling, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375211/
https://www.ncbi.nlm.nih.gov/pubmed/30809375
http://dx.doi.org/10.1186/s13569-019-0113-6

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