Cargando…

Widespread RNA editing dysregulation in brains from autistic individuals

Transcriptomic analyses of postmortem brains have begun to elucidate the molecular abnormalities in autism spectrum disorder (ASD). However, a crucial pathway involved in synaptic development, RNA editing, has not yet been studied on a genome-wide scale. Here, we profiled global patterns of adenosin...

Descripción completa

Detalles Bibliográficos
Autores principales: Tran, Stephen S., Jun, Hyun-Ik, Bahn, Jae Hoon, Azghadi, Adel, Ramaswami, Gokul, Van Nostrand, Eric L., Nguyen, Thai B., Hsiao, Yun-Hua E., Lee, Changhoon, Pratt, Gabriel A., Martínez-Cerdeño, Verónica, Hagerman, Randi J., Yeo, Gene W., Geschwind, Daniel H., Xiao, Xinshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375307/
https://www.ncbi.nlm.nih.gov/pubmed/30559470
http://dx.doi.org/10.1038/s41593-018-0287-x

Ejemplares similares