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Widespread RNA editing dysregulation in brains from autistic individuals
Transcriptomic analyses of postmortem brains have begun to elucidate the molecular abnormalities in autism spectrum disorder (ASD). However, a crucial pathway involved in synaptic development, RNA editing, has not yet been studied on a genome-wide scale. Here, we profiled global patterns of adenosin...
Autores principales: | Tran, Stephen S., Jun, Hyun-Ik, Bahn, Jae Hoon, Azghadi, Adel, Ramaswami, Gokul, Van Nostrand, Eric L., Nguyen, Thai B., Hsiao, Yun-Hua E., Lee, Changhoon, Pratt, Gabriel A., Martínez-Cerdeño, Verónica, Hagerman, Randi J., Yeo, Gene W., Geschwind, Daniel H., Xiao, Xinshu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375307/ https://www.ncbi.nlm.nih.gov/pubmed/30559470 http://dx.doi.org/10.1038/s41593-018-0287-x |
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