Alternative (backdoor) androgen production and masculinization in the human fetus

Masculinization of the external genitalia in humans is dependent on formation of 5α-dihydrotestosterone (DHT) through both the canonical androgenic pathway and an alternative (backdoor) pathway. The fetal testes are essential for canonical androgen production, but little is known about the synthesis...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Shaughnessy, Peter J., Antignac, Jean Philippe, Le Bizec, Bruno, Morvan, Marie-Line, Svechnikov, Konstantin, Söder, Olle, Savchuk, Iuliia, Monteiro, Ana, Soffientini, Ugo, Johnston, Zoe C., Bellingham, Michelle, Hough, Denise, Walker, Natasha, Filis, Panagiotis, Fowler, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375548/
https://www.ncbi.nlm.nih.gov/pubmed/30763313
http://dx.doi.org/10.1371/journal.pbio.3000002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375548/
https://www.ncbi.nlm.nih.gov/pubmed/30763313
http://dx.doi.org/10.1371/journal.pbio.3000002

Ejemplares similares