The cAMP effectors, Rap2b and EPAC, are involved in the regulation of the development of the Coxiella burnetii containing vacuole by altering the fusogenic capacity of the vacuole

Cyclic Adenosine 3′,5′-monophosphate (cAMP) is a key second messenger known to directly regulate not only the protein kinase A (PKA) activity but also other important molecules such as the exchange protein activated by cAMP (EPAC), which is as a guanine nucleotide exchange factor (GEF) of the low mo...

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Detalles Bibliográficos
Autores principales: Mansilla Pareja, María Eugenia, Gaurón, Maria Celeste, Robledo, Esteban, Aguilera, Milton Osmar, Colombo, María Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375611/
https://www.ncbi.nlm.nih.gov/pubmed/30763357
http://dx.doi.org/10.1371/journal.pone.0212202

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