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Conformational regulation of Escherichia coli DNA polymerase V by RecA and ATP
Mutagenic translesion DNA polymerase V (UmuD′(2)C) is induced as part of the DNA damage-induced SOS response in Escherichia coli, and is subjected to multiple levels of regulation. The UmuC subunit is sequestered on the cell membrane (spatial regulation) and enters the cytosol after forming a UmuD′(...
Autores principales: | Jaszczur, Malgorzata M., Vo, Dan D., Stanciauskas, Ramunas, Bertram, Jeffrey G., Sikand, Adhirath, Cox, Michael M., Woodgate, Roger, Mak, Chi H., Pinaud, Fabien, Goodman, Myron F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375631/ https://www.ncbi.nlm.nih.gov/pubmed/30716079 http://dx.doi.org/10.1371/journal.pgen.1007956 |
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