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Mapping DNA sequence to transcription factor binding energy in vivo

Despite the central importance of transcriptional regulation in biology, it has proven difficult to determine the regulatory mechanisms of individual genes, let alone entire gene networks. It is particularly difficult to decipher the biophysical mechanisms of transcriptional regulation in living cel...

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Detalles Bibliográficos
Autores principales: Barnes, Stephanie L., Belliveau, Nathan M., Ireland, William T., Kinney, Justin B., Phillips, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375646/
https://www.ncbi.nlm.nih.gov/pubmed/30716072
http://dx.doi.org/10.1371/journal.pcbi.1006226