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A novel cell-free method to culture Schistosoma mansoni from cercariae to juvenile worm stages for in vitro drug testing
BACKGROUND: The arsenal in anthelminthic treatment against schistosomiasis is limited and relies almost exclusively on a single drug, praziquantel (PZQ). Thus, resistance to PZQ could constitute a major threat. Even though PZQ is potent in killing adult worms, its activity against earlier stages is...
Autores principales: | Frahm, Sören, Anisuzzaman, Anisuzzaman, Prodjinotho, Ulrich Fabien, Vejzagić, Nermina, Verschoor, Admar, Prazeres da Costa, Clarissa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375649/ https://www.ncbi.nlm.nih.gov/pubmed/30689639 http://dx.doi.org/10.1371/journal.pntd.0006590 |
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