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Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia
OBJECTIVE: Morphine is a commonly used drug in encephalopathic neonates treated with therapeutic hypothermia after perinatal asphyxia. Pharmacokinetics and optimal dosing of morphine in this population are largely unknown. The objective of this study was to describe pharmacokinetics of morphine and...
Autores principales: | Favié, Laurent M. A., Groenendaal, Floris, van den Broek, Marcel P. H., Rademaker, Carin M. A., de Haan, Timo R., van Straaten, Henrica L. M., Dijk, Peter H., van Heijst, Arno, Dudink, Jeroen, Dijkman, Koen P., Rijken, Monique, Zonnenberg, Inge A., Cools, Filip, Zecic, Alexandra, van der Lee, Johanna H., Nuytemans, Debbie H. G. M., van Bel, Frank, Egberts, Toine C. G., Huitema, Alwin D. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375702/ https://www.ncbi.nlm.nih.gov/pubmed/30763356 http://dx.doi.org/10.1371/journal.pone.0211910 |
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