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Negative reciprocity, not ordered assembly, underlies the interaction of Sox2 and Oct4 on DNA
The mode of interaction of transcription factors (TFs) on eukaryotic genomes remains a matter of debate. Single-molecule data in living cells for the TFs Sox2 and Oct4 were previously interpreted as evidence of ordered assembly on DNA. However, the quantity that was calculated does not determine bin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375704/ https://www.ncbi.nlm.nih.gov/pubmed/30762521 http://dx.doi.org/10.7554/eLife.41017 |