RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation

Receptor-interacting protein kinase (RIPK) 1 functions as a key mediator of tissue homeostasis via formation of Caspase-8 activating ripoptosome complexes, positively and negatively regulating apoptosis, necroptosis, and inflammation. Here, we report an unanticipated cell-death- and inflammation-ind...

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Detalles Bibliográficos
Autores principales: Liccardi, Gianmaria, Ramos Garcia, Laura, Tenev, Tencho, Annibaldi, Alessandro, Legrand, Arnaud J., Robertson, David, Feltham, Rebecca, Anderton, Holly, Darding, Maurice, Peltzer, Nieves, Dannappel, Marius, Schünke, Hannah, Fava, Luca L., Haschka, Manuel D., Glatter, Timo, Nesvizhskii, Alexey, Schmidt, Alexander, Harris, Philip A., Bertin, John, Gough, Peter J., Villunger, Andreas, Silke, John, Pasparakis, Manolis, Bianchi, Katiuscia, Meier, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375735/
https://www.ncbi.nlm.nih.gov/pubmed/30598363
http://dx.doi.org/10.1016/j.molcel.2018.11.010

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