Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality

Neutrophils clear viruses, but excessive neutrophil responses induce tissue injury and worsen disease. Aging increases mortality to influenza infection; however, whether this is due to impaired viral clearance or a pathological host immune response is unknown. Here, we show that aged mice have highe...

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Detalles Bibliográficos
Autores principales: Kulkarni, Upasana, Zemans, Rachel L., Smith, Candice A., Wood, Sherri, Deng, Jane C., Goldstein, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375784/
https://www.ncbi.nlm.nih.gov/pubmed/30617300
http://dx.doi.org/10.1038/s41385-018-0115-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375784/
https://www.ncbi.nlm.nih.gov/pubmed/30617300
http://dx.doi.org/10.1038/s41385-018-0115-3

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