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Excessive neutrophil levels in the lung underlie the age-associated increase in influenza mortality
Neutrophils clear viruses, but excessive neutrophil responses induce tissue injury and worsen disease. Aging increases mortality to influenza infection; however, whether this is due to impaired viral clearance or a pathological host immune response is unknown. Here, we show that aged mice have highe...
Autores principales: | Kulkarni, Upasana, Zemans, Rachel L., Smith, Candice A., Wood, Sherri, Deng, Jane C., Goldstein, Daniel R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375784/ https://www.ncbi.nlm.nih.gov/pubmed/30617300 http://dx.doi.org/10.1038/s41385-018-0115-3 |
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