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Treatment Outcome of Intracranial Tumor Embolization in Japan: Japanese Registry of NeuroEndovascular Therapy 3 (JR-NET3)
Embolization for intracranial tumor is performed as a standard endovascular treatment. A retrospective, multicenter, observational study was conducted to clarify the nature, frequency, and risk factors of complications in intracranial tumor embolization. Patients were derived from the Japanese Regis...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Neurosurgical Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375818/ https://www.ncbi.nlm.nih.gov/pubmed/30686813 http://dx.doi.org/10.2176/nmc.st.2018-0220 |
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author | SUGIU, Kenji HISHIKAWA, Tomohito MURAI, Satoshi TAKAHASHI, Yu KIDANI, Naoya NISHIHIRO, Shingo HIRAMATSU, Masafumi DATE, Isao SATOW, Tetsu IIHARA, Koji SAKAI, Nobuyuki |
author_facet | SUGIU, Kenji HISHIKAWA, Tomohito MURAI, Satoshi TAKAHASHI, Yu KIDANI, Naoya NISHIHIRO, Shingo HIRAMATSU, Masafumi DATE, Isao SATOW, Tetsu IIHARA, Koji SAKAI, Nobuyuki |
author_sort | SUGIU, Kenji |
collection | PubMed |
description | Embolization for intracranial tumor is performed as a standard endovascular treatment. A retrospective, multicenter, observational study was conducted to clarify the nature, frequency, and risk factors of complications in intracranial tumor embolization. Patients were derived from the Japanese Registry of NeuroEndovascular Therapy (JR-NET3) using data taken from January 2010 through December 2014 in Japan. A total of 40,169 patients were enrolled in JR-NET3, of which, 1,545 patients (3.85%) with intracranial tumors underwent embolization. The primary end point was the proportion of patients with a modified Rankin scale (mRS) score of 0–2 (independency) at 30 days after embolization. The secondary end point was the occurrence of complications related to the procedures. The risk factors of the development of complications were analyzed. The proportion of patients with mRS scores ≤2 at 30 days after procedure was 89.5%. Complications occurred in 57 of the 1544 patients (3.7%). Multivariate analysis showed that target vessels other than external carotid artery (ECA) (OR, 3.56; 95% CI, 2.03–6.25; P <0.001) and use of liquid material (OR, 2.65; 95% CI, 1.50–4.68; P <0.001) were significantly associated with the development of complications. In JR-NET3, the primary end point was 89.5%, and the procedure-related complication rate was 3.7%. Embolization from other than ECA was significant risk factor of the complications. In addition, increasing usage of liquid embolic material worsened the risk of complications. |
format | Online Article Text |
id | pubmed-6375818 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Japan Neurosurgical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-63758182019-02-15 Treatment Outcome of Intracranial Tumor Embolization in Japan: Japanese Registry of NeuroEndovascular Therapy 3 (JR-NET3) SUGIU, Kenji HISHIKAWA, Tomohito MURAI, Satoshi TAKAHASHI, Yu KIDANI, Naoya NISHIHIRO, Shingo HIRAMATSU, Masafumi DATE, Isao SATOW, Tetsu IIHARA, Koji SAKAI, Nobuyuki Neurol Med Chir (Tokyo) Special Topic Embolization for intracranial tumor is performed as a standard endovascular treatment. A retrospective, multicenter, observational study was conducted to clarify the nature, frequency, and risk factors of complications in intracranial tumor embolization. Patients were derived from the Japanese Registry of NeuroEndovascular Therapy (JR-NET3) using data taken from January 2010 through December 2014 in Japan. A total of 40,169 patients were enrolled in JR-NET3, of which, 1,545 patients (3.85%) with intracranial tumors underwent embolization. The primary end point was the proportion of patients with a modified Rankin scale (mRS) score of 0–2 (independency) at 30 days after embolization. The secondary end point was the occurrence of complications related to the procedures. The risk factors of the development of complications were analyzed. The proportion of patients with mRS scores ≤2 at 30 days after procedure was 89.5%. Complications occurred in 57 of the 1544 patients (3.7%). Multivariate analysis showed that target vessels other than external carotid artery (ECA) (OR, 3.56; 95% CI, 2.03–6.25; P <0.001) and use of liquid material (OR, 2.65; 95% CI, 1.50–4.68; P <0.001) were significantly associated with the development of complications. In JR-NET3, the primary end point was 89.5%, and the procedure-related complication rate was 3.7%. Embolization from other than ECA was significant risk factor of the complications. In addition, increasing usage of liquid embolic material worsened the risk of complications. The Japan Neurosurgical Society 2019-02 2019-01-26 /pmc/articles/PMC6375818/ /pubmed/30686813 http://dx.doi.org/10.2176/nmc.st.2018-0220 Text en © 2019 The Japan Neurosurgical Society This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ |
spellingShingle | Special Topic SUGIU, Kenji HISHIKAWA, Tomohito MURAI, Satoshi TAKAHASHI, Yu KIDANI, Naoya NISHIHIRO, Shingo HIRAMATSU, Masafumi DATE, Isao SATOW, Tetsu IIHARA, Koji SAKAI, Nobuyuki Treatment Outcome of Intracranial Tumor Embolization in Japan: Japanese Registry of NeuroEndovascular Therapy 3 (JR-NET3) |
title | Treatment Outcome of Intracranial Tumor Embolization in Japan: Japanese Registry of NeuroEndovascular Therapy 3 (JR-NET3) |
title_full | Treatment Outcome of Intracranial Tumor Embolization in Japan: Japanese Registry of NeuroEndovascular Therapy 3 (JR-NET3) |
title_fullStr | Treatment Outcome of Intracranial Tumor Embolization in Japan: Japanese Registry of NeuroEndovascular Therapy 3 (JR-NET3) |
title_full_unstemmed | Treatment Outcome of Intracranial Tumor Embolization in Japan: Japanese Registry of NeuroEndovascular Therapy 3 (JR-NET3) |
title_short | Treatment Outcome of Intracranial Tumor Embolization in Japan: Japanese Registry of NeuroEndovascular Therapy 3 (JR-NET3) |
title_sort | treatment outcome of intracranial tumor embolization in japan: japanese registry of neuroendovascular therapy 3 (jr-net3) |
topic | Special Topic |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375818/ https://www.ncbi.nlm.nih.gov/pubmed/30686813 http://dx.doi.org/10.2176/nmc.st.2018-0220 |
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