Genital Infiltrations of CD4(+) and CD8(+) T Lymphocytes, IgA(+) and IgG(+) Plasma Cells and Intra-Mucosal Lymphoid Follicles Associate With Protection Against Genital Chlamydia trachomatis Infection in Minipigs Intramuscularly Immunized With UV-Inactivated Bacteria Adjuvanted With CAF01

The development of a vaccine against genital chlamydia in women is advancing, and the evaluation of in situ immune responses following vaccination and challenge infections is crucial for development of a safe and protective vaccine. This study employs the sexually mature minipig model to characteriz...

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Detalles Bibliográficos
Autores principales: Erneholm, Karin, Lorenzen, Emma, Bøje, Sarah, Olsen, Anja Weinreich, Jungersen, Gregers, Jensen, Henrik E., Cassidy, Joseph P., Andersen, Peter, Agerholm, Jørgen S., Follmann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375829/
https://www.ncbi.nlm.nih.gov/pubmed/30800114
http://dx.doi.org/10.3389/fmicb.2019.00197

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