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Loss of TrkB Signaling Due to Status Epilepticus Induces a proBDNF-Dependent Cell Death

Neurotrophins (NTs) are secretory proteins that bind to target receptors and influence many cellular functions, such as cell survival and cell death in neurons. The mammalian NT brain-derived neurotrophic factor (matBDNF) is the C-terminal mature form released by cleavage from the proBDNF precursor....

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Detalles Bibliográficos
Autores principales: Montroull, Laura Ester, Danelon, Víctor, Cragnolini, Andrea Beatriz, Mascó, Daniel Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375841/
https://www.ncbi.nlm.nih.gov/pubmed/30800056
http://dx.doi.org/10.3389/fncel.2019.00004