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Transition from post‐capillary pulmonary hypertension to combined pre‐ and post‐capillary pulmonary hypertension in swine: a key role for endothelin

KEY POINTS: Passive, isolated post‐capillary pulmonary hypertension (PH) secondary to left heart disease may progress to combined pre‐ and post‐capillary or ‘active’ PH. This ‘activation’ of post‐capillary PH significantly increases morbidity and mortality, and is still incompletely understood. In t...

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Detalles Bibliográficos
Autores principales: van Duin, Richard W. B., Stam, Kelly, Cai, Zongye, Uitterdijk, André, Garcia‐Alvarez, Ana, Ibanez, Borja, Danser, A. H. Jan, Reiss, Irwin K. M., Duncker, Dirk J., Merkus, Daphne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375874/
https://www.ncbi.nlm.nih.gov/pubmed/29799120
http://dx.doi.org/10.1113/JP275987