A mutagenesis analysis of Tim50, the major receptor of the TIM23 complex, identifies regions that affect its interaction with Tim23

Maintenance of the mitochondrial proteome depends on import of newly made proteins from the cytosol. More than half of mitochondrial proteins are made as precursor proteins with N-terminal extensions called presequences and use the TIM23 complex for translocation into the matrix, the inner mitochond...

Descripción completa

Detalles Bibliográficos
Autores principales: Dayan, Dana, Bandel, May, Günsel, Umut, Nussbaum, Inbal, Prag, Gali, Mokranjac, Dejana, Neupert, Walter, Azem, Abdussalam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375917/
https://www.ncbi.nlm.nih.gov/pubmed/30765764
http://dx.doi.org/10.1038/s41598-018-38353-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375917/
https://www.ncbi.nlm.nih.gov/pubmed/30765764
http://dx.doi.org/10.1038/s41598-018-38353-1

Ejemplares similares