Targeting Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor 2 (HER2) Expressing Bladder Cancer Using Combination Photoimmunotherapy (PIT)

Bladder cancer (BC) is heterogeneous and expresses various cell surface targets. Photoimmunotherapy (PIT) involves monoclonal antibodies (MAbs) conjugated to a photoabsorber (PA), IR Dye 700Dx, and then activated by near infra-red light (NIR) to specifically target tumors. We have demonstrated that...

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Detalles Bibliográficos
Autores principales: Siddiqui, Mohammad R., Railkar, Reema, Sanford, Thomas, Crooks, Daniel R., Eckhaus, Michael A., Haines, Diana, Choyke, Peter L., Kobayashi, Hisataka, Agarwal, Piyush K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375935/
https://www.ncbi.nlm.nih.gov/pubmed/30765854
http://dx.doi.org/10.1038/s41598-019-38575-x

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