MG132 protects against renal dysfunction by regulating Akt-mediated inflammation in diabetic nephropathy

Diabetic nephropathy (DN), the leading cause of end-stage renal disease (ESRD). To date, mounting evidence has shown that inflammation may contribute to the pathogenesis of DN. Recent reports have shown that proteasome inhibitors display cytoprotection by reducing the phosphorylation of Akt, a serin...

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Detalles Bibliográficos
Autores principales: Zeng, Wei, Qi, Wei, Mu, Jiao, Wei, Yi, Yang, Li-Ling, Zhang, Qian, Wu, Qiong, Tang, Jian-Ying, Feng, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375942/
https://www.ncbi.nlm.nih.gov/pubmed/30765727
http://dx.doi.org/10.1038/s41598-018-38425-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375942/
https://www.ncbi.nlm.nih.gov/pubmed/30765727
http://dx.doi.org/10.1038/s41598-018-38425-2

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