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Network controllability analysis of intracellular signalling reveals viruses are actively controlling molecular systems

In recent years control theory has been applied to biological systems with the aim of identifying the minimum set of molecular interactions that can drive the network to a required state. However, in an intra-cellular network it is unclear how control can be achieved in practice. To address this lim...

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Detalles Bibliográficos
Autores principales: Ravindran, Vandana, Nacher, Jose C., Akutsu, Tatsuya, Ishitsuka, Masayuki, Osadcenco, Adrian, Sunitha, V., Bagler, Ganesh, Schwartz, Jean-Marc, Robertson, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375943/
https://www.ncbi.nlm.nih.gov/pubmed/30765882
http://dx.doi.org/10.1038/s41598-018-38224-9