Cargando…

Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart

Hemodynamic stress on the mammalian heart results in compensatory hypertrophy and activation of the unfolded protein response through activating transcription factor 6α (ATF6α) in cardiac myocytes, but the roles of ATF6α or the related transcription factor ATF6β in regulating this hypertrophic respo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Correll, Robert N., Grimes, Kelly M., Prasad, Vikram, Lynch, Jeffrey M., Khalil, Hadi, Molkentin, Jeffery D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375966/ https://www.ncbi.nlm.nih.gov/pubmed/30765833 http://dx.doi.org/10.1038/s41598-019-39515-5

Ejemplares similares

Paradoxical roles of ATF6α and ATF6β in modulating disease severity caused by mutations in collagen X
por: Forouhan, M., et al.
Publicado: (2018)

Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress
por: Gallagher, Ciara M, et al.
Publicado: (2016)

Expression and regulation of ATF6α in the mouse uterus during embryo implantation
por: Xiong, Yongjie, et al.
Publicado: (2016)

Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy
por: Vanhoutte, Davy, et al.
Publicado: (2021)

ATF6 as a Nodal Regulator of Proteostasis in the Heart
por: Glembotski, Christopher C., et al.
Publicado: (2020)

Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABA(A) receptors
por: Wang, Meng, et al.
Publicado: (2022)

Beam Jitter Studies at ATF and ATF2
por: Pfingstner, Jürgen, et al.
Publicado: (2013)

Mutation of ATF6 causes autosomal recessive achromatopsia
por: Ansar, Muhammad, et al.
Publicado: (2015)

Investigating the involvement of the ATF6α pathway of the unfolded protein response in adipogenesis
por: Lowe, C E, et al.
Publicado: (2012)

ATF6α regulates morphological changes associated with senescence in human fibroblasts
por: Druelle, Clémentine, et al.
Publicado: (2016)

Atf6α impacts cell number by influencing survival, death and proliferation
por: Sharma, Rohit B., et al.
Publicado: (2019)

Characterization of Retinal Structure in ATF6-Associated Achromatopsia
por: Mastey, Rebecca R., et al.
Publicado: (2019)

Gremlin-1 Promotes Colorectal Cancer Cell Metastasis by Activating ATF6 and Inhibiting ATF4 Pathways
por: Li, Ruohan, et al.
Publicado: (2022)

Scleral PERK and ATF6 as targets of myopic axial elongation of mouse eyes
por: Ikeda, Shin-ichi, et al.
Publicado: (2022)

A lifetime of stress: ATF6 in development and homeostasis
por: Hillary, Robert F., et al.
Publicado: (2018)

KLF6 Induces Apoptosis in Human Lens Epithelial Cells Through the ATF4-ATF3-CHOP Axis
por: Tian, Fang, et al.
Publicado: (2020)

Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins
por: Paxman, Ryan, et al.
Publicado: (2018)

ERp18 regulates activation of ATF6α during unfolded protein response
por: Oka, Ojore BV, et al.
Publicado: (2019)

Flurochloridone Induced Cell Apoptosis via ER Stress and eIF2α-ATF4/ATF6-CHOP-Bim/Bax Signaling Pathways in Mouse TM4 Sertoli Cells
por: Zhang, Fen, et al.
Publicado: (2022)

Genetic Interactions Between Aspergillus fumigatus Basic Leucine Zipper (bZIP) Transcription Factors AtfA, AtfB, AtfC, and AtfD
por: Silva, Lilian Pereira, et al.
Publicado: (2021)

ER Stress Activates the TOR Pathway through Atf6
por: Allen, Dylan, et al.
Publicado: (2018)

Mineral trioxide aggregate induces osteoblastogenesis via Atf6
por: Maeda, Toyonobu, et al.
Publicado: (2015)

Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs
por: Örd, Tiit, et al.
Publicado: (2023)

ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial Repair
por: Meijer, Bartolomeus J., et al.
Publicado: (2020)

Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake
por: Kobylewski, Sarah E., et al.
Publicado: (2016)

Designing Novel Therapies to Mend Broken Hearts: ATF6 and Cardiac Proteostasis
por: Blackwood, Erik A., et al.
Publicado: (2020)

A Cytoplasmic Negative Regulator Isoform of ATF7 Impairs ATF7 and ATF2 Phosphorylation and Transcriptional Activity
por: Diring, Jessica, et al.
Publicado: (2011)

Loss of ATF6α in a human carcinoma cell line is compensated not by its paralogue ATF6β but by sustained activation of the IRE1 and PERK arms for tumor growth in nude mice
por: Jin, Shengyu, et al.
Publicado: (2023)

ATF2 COMMISSIONING
por: Seryi, A, et al.
Publicado: (2010)

ATF6α contributes to rheumatoid arthritis by inducing inflammatory cytokine production and apoptosis resistance
por: Ge, Luna, et al.
Publicado: (2022)

ATF6 Activation Reduces Amyloidogenic Transthyretin Secretion through Increased Interactions with Endoplasmic Reticulum Proteostasis Factors
por: Mesgarzadeh, Jaleh S., et al.
Publicado: (2022)

Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis
por: Blackwood, Erik A., et al.
Publicado: (2019)

Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress
por: Sundaram, Arunkumar, et al.
Publicado: (2018)

ATF linac commissioning
por: Hayano, H
Publicado: (1996)

Timing system of the ATF
por: Naito, T, et al.
Publicado: (1997)

ATF report 2020
por: Aryshev, Alexander, et al.
Publicado: (2020)

Atf-6 Regulates Lifespan through ER-Mitochondrial Calcium Homeostasis
por: Burkewitz, Kristopher, et al.
Publicado: (2020)

Beneficial effects of neuronal ATF6 activation in permanent ischemic stroke
por: Li, Xuan, et al.
Publicado: (2022)

ATF6α Activation Enhances Survival against Chemotherapy and Serves as a Prognostic Indicator in Osteosarcoma()()
por: Yarapureddy, Suma, et al.
Publicado: (2019)

Normal tissue homeostasis and impairment of selective inflammatory responses in dendritic cells deficient for ATF6α
por: Gutiérrez-Ballesteros, Francisca, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3orfhcprk0nduhibmjhqhp4vvf