The co-inhibitory molecule PD-L1 contributes to regulatory T cell-mediated protection in murine crescentic glomerulonephritis

Immune-mediated glomerular diseases like crescentic glomerulonephritis (cGN) are driven by inappropriately regulated cellular and humoral immune responses subsequently leading to renal tissue injury. Recent studies demonstrated the crucial role for regulatory T cells (Tregs) in suppressing pathogeni...

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Detalles Bibliográficos
Autores principales: Neumann, Katrin, Ostmann, Annett, Breda, Philippe Christophe, Ochel, Aaron, Tacke, Frank, Paust, Hans-Joachim, Panzer, Ulf, Tiegs, Gisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375967/
https://www.ncbi.nlm.nih.gov/pubmed/30765734
http://dx.doi.org/10.1038/s41598-018-38432-3

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