Macrophage Migration Inhibitory Factor Acts as the Potential Target of a Newly Synthesized Compound, 1-(9′-methyl-3′-carbazole)-3, 4-dihydro-β-carboline

For a newly synthesized compound, identifying its target protein is a slow but pivotal step toward understand its pharmacologic mechanism. In this study, we systemically synthesized novel manzamine derivatives and chose 1-(9′-methyl-3′-carbazole)-3, 4-dihydro-β-carboline (MCDC) as an example to iden...

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Detalles Bibliográficos
Autores principales: Ko, Pin-Hao, Shen, Ya-Ching, Murugan, Kaliyappan, Huang, Chiung-Wei, Sivakumar, Govindan, Pal, Pinki, Liao, Chia-Ching, Luo, Kai-Shin, Chuang, Eric Y., Tsai, Mong-Hsun, Lai, Liang-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375994/
https://www.ncbi.nlm.nih.gov/pubmed/30765775
http://dx.doi.org/10.1038/s41598-019-38590-y

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