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High-resolution respirometry in human endomyocardial biopsies shows reduced ventricular oxidative capacity related to heart failure

The lifetime risk of developing heart failure is approximately 20%, and survival rates remain poor. Myocardial mitochondrial function has been suggested to play a pivotal role in heart failure pathophysiology. Human studies on ex vivo mitochondrial function have mostly been limited to atrial tissue...

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Detalles Bibliográficos
Autores principales: Scheiber, Daniel, Jelenik, Tomas, Zweck, Elric, Horn, Patrick, Schultheiss, Heinz-Peter, Lassner, Dirk, Boeken, Udo, Saeed, Diyar, Kelm, Malte, Roden, Michael, Westenfeld, Ralf, Szendroedi, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376010/
https://www.ncbi.nlm.nih.gov/pubmed/30765687
http://dx.doi.org/10.1038/s12276-019-0214-6