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Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions
Adenovirus based vectors are of increasing importance for wide ranging therapeutic applications. As vaccines, vectors derived from human adenovirus species D serotypes 26 and 48 (HAdV-D26/48) are demonstrating promising efficacy as protective platforms against infectious diseases. Significant clinic...
Autores principales: | Baker, Alexander T., Greenshields-Watson, Alexander, Coughlan, Lynda, Davies, James A., Uusi-Kerttula, Hanni, Cole, David K., Rizkallah, Pierre J., Parker, Alan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376029/ https://www.ncbi.nlm.nih.gov/pubmed/30765704 http://dx.doi.org/10.1038/s41467-019-08599-y |
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