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Hereditary Hemochromatosis Associations with Frailty, Sarcopenia and Chronic Pain: Evidence from 200,975 Older UK Biobank Participants
BACKGROUND: Iron is essential for life but contributes to oxidative damage. In Northern-European ancestry populations, HFE gene C282Y mutations are relatively common (0.3%–0.6% rare homozygote prevalence) and associated with excessive iron absorption, fatigue, diabetes, arthritis, and liver disease,...
Autores principales: | Tamosauskaite, Jone, Atkins, Janice L, Pilling, Luke C, Kuo, Chia-Ling, Kuchel, George A, Ferrucci, Luigi, Melzer, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376086/ https://www.ncbi.nlm.nih.gov/pubmed/30657865 http://dx.doi.org/10.1093/gerona/gly270 |
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