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Cold Tumors: A Therapeutic Challenge for Immunotherapy
Therapeutic monoclonal antibodies targeting immune checkpoints (ICPs) have changed the treatment landscape of many tumors. However, response rate remains relatively low in most cases. A major factor involved in initial resistance to ICP inhibitors is the lack or paucity of tumor T cell infiltration,...
Autores principales: | Bonaventura, Paola, Shekarian, Tala, Alcazer, Vincent, Valladeau-Guilemond, Jenny, Valsesia-Wittmann, Sandrine, Amigorena, Sebastian, Caux, Christophe, Depil, Stéphane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376112/ https://www.ncbi.nlm.nih.gov/pubmed/30800125 http://dx.doi.org/10.3389/fimmu.2019.00168 |
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